Website
https://dataportal.arc.gov.au/NCGP/API/grants/DP160103958
Funding Status
Closed
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Funded Activity Summary
Unravelling the principles of bilateral brain wiring. This project seeks to investigate the molecular principles of brain wiring in mammals and how small changes can generate complex outcomes. Neurons in the mammalian brain must be precisely wired together for the brain to function correctly. The project aims to identify the molecular and cellular rules governing commissural wiring in the mammalian cortex to determine how the largest fibre tract in the human brain, the corpus callosum, evolved. This may have involved modifications in mechanisms affecting axon guidance that differ between placentals and marsupials. The project investigates the regulatory gene networks determining commissural neuron fate, the regulation of axon guidance components, and the influence of surrounding brain tissue on the development of commissural connections.Funded Activity Details
Start Date: 2016
End Date: 12-2019
Funding Scheme: Discovery Projects
Funding Amount: $592,700.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Zoology | Animal Cell and Molecular Biology | Animal Neurobiology |
