Taking advice: Limits and potentials of social decision-making in older age. Older adults are increasingly victims of financial fraud and abuse. While well-intentioned advice has the potential to improve financial decision-making, ill-intentioned advice can lead to exploitation. This project will use extensive behavioural testing to establish the factors governing how much weight older adults give to advice depending on the type of advisor, the type of advice, and feedback about advice quality. ....Taking advice: Limits and potentials of social decision-making in older age. Older adults are increasingly victims of financial fraud and abuse. While well-intentioned advice has the potential to improve financial decision-making, ill-intentioned advice can lead to exploitation. This project will use extensive behavioural testing to establish the factors governing how much weight older adults give to advice depending on the type of advisor, the type of advice, and feedback about advice quality. The outcome will be a model of the influence of advice on decision-making in ageing. This will provide an evidence base to create best practice guidelines, interventions, and decision aids that will reduce exploitation and increase the independence and wellbeing of Australia’s rapidly ageing population.Read moreRead less
Hippocampal regulation of goal-directed decision-making. The hippocampus is a part of the brain that is central to learning and memory yet little is known about its role in decision-making. It is the aim of this application to provide the first detailed, causal evidence of hippocampal regulation of decision-making. This is significant because many mental health disorders and dementias that involve decision-making deficits are characterised by hippocampal dysfunction, but any direct link between ....Hippocampal regulation of goal-directed decision-making. The hippocampus is a part of the brain that is central to learning and memory yet little is known about its role in decision-making. It is the aim of this application to provide the first detailed, causal evidence of hippocampal regulation of decision-making. This is significant because many mental health disorders and dementias that involve decision-making deficits are characterised by hippocampal dysfunction, but any direct link between these factors is unknown. The outcomes of the current grant will provide the first evidence of that link, thus providing deeper understanding of the neurophysiological mechanisms of these disorders, which could eventuate in the creation of more beneficial treatments. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100790
Funder
Australian Research Council
Funding Amount
$419,308.00
Summary
Understanding how the brain combines sensory information. The ease with which we perceive the external world belies the complexity involved in integrating different sensory inputs. How does the brain achieve this fundamental operation? The project will address this question using a multidisciplinary approach that combines computational modelling, brain imaging, and psychophysical techniques. The expected outcomes of the project are a better understanding of how people perceive the world through ....Understanding how the brain combines sensory information. The ease with which we perceive the external world belies the complexity involved in integrating different sensory inputs. How does the brain achieve this fundamental operation? The project will address this question using a multidisciplinary approach that combines computational modelling, brain imaging, and psychophysical techniques. The expected outcomes of the project are a better understanding of how people perceive the world through optimal integration of sensory cues. In addition to advancing basic scientific knowledge, the findings will illuminate perceptual anomalies in normally developing children and will provide a foundation for reducing a debilitating side effect of virtual reality systems known as ‘cybersickness’.Read moreRead less
A comprehensive framework for modelling the human connectome. The human brain is an extraordinarily complex network of interconnected cells. This project aims to use mathematical modelling and brain imaging to uncover key principles of network wiring in the human brain. Using an interdisciplinary approach that combines elements of neuroscience, genetics, physics, and psychology, the project will result in a new, rigorous framework for testing competing theories of brain development, the identifi ....A comprehensive framework for modelling the human connectome. The human brain is an extraordinarily complex network of interconnected cells. This project aims to use mathematical modelling and brain imaging to uncover key principles of network wiring in the human brain. Using an interdisciplinary approach that combines elements of neuroscience, genetics, physics, and psychology, the project will result in a new, rigorous framework for testing competing theories of brain development, the identification of key wiring principles for developing brains, and an understanding of how these principles shape behaviour. This work will shed new light on the developmental processes that underlie human behaviour and disease.Read moreRead less
Neuronal and behavioural correlates of sensory adaptation. Sensory systems adapt to the statistics of their environment, and the consequences of this adaptation are evident in neuronal activity and in animal’s behaviour. This project will employ a novel paradigm to characterise how adaptation changes the response properties of individual sensory neurons to improve efficiency of information transmission.
Extinction of conditioned responding: Learning from the evidence of absence. When animals or people learn that a cue, or their own action, is followed by something important, they respond in anticipation of the outcome or to control it. This project investigates how these learned responses can be reduced (“extinguished”) when the conditions that established them change. It will help solve 2 outstanding theoretical and practical problems: what makes some learned behaviours resistant to extinction ....Extinction of conditioned responding: Learning from the evidence of absence. When animals or people learn that a cue, or their own action, is followed by something important, they respond in anticipation of the outcome or to control it. This project investigates how these learned responses can be reduced (“extinguished”) when the conditions that established them change. It will help solve 2 outstanding theoretical and practical problems: what makes some learned behaviours resistant to extinction or prone to relapse after being extinguished? The project will identify the factors that are most directly responsible for resistance and relapse. This could pave the way to finding solutions for the major problems that bedevil therapies designed to treat human behavioural disorders, such as addictions, gambling, and anxietyRead moreRead less
Assessment of circadian and light interactions in adolescent sleepiness. This project aims to examine the relative contributions of multiple biological clock and sleep factors that may be linked to cognitive function and sleepiness in adolescents. Over 70 per cent of adolescents in Australia experience insufficient sleep. Cross-sectional studies have shown that insufficient sleep and mistimed sleep lead to reduced cognitive function. The project intends to identify specific sleep and circadian m ....Assessment of circadian and light interactions in adolescent sleepiness. This project aims to examine the relative contributions of multiple biological clock and sleep factors that may be linked to cognitive function and sleepiness in adolescents. Over 70 per cent of adolescents in Australia experience insufficient sleep. Cross-sectional studies have shown that insufficient sleep and mistimed sleep lead to reduced cognitive function. The project intends to identify specific sleep and circadian markers that are linked to academic performance, and generate innovative algorithms that predict these associations. The project will provide new knowledge to drive prevention and early intervention programs that use sleep-wake and light exposure information to improve sleep quality.Read moreRead less
When, why, and how well do we regulate other people's emotions? This project aims to understand when and why people attempt to regulate others' emotions, and to evaluate which regulation processes are most effective. We will study regulation attempts as they occur over minutes, days, and months in interactions between romantic couples and between nurse co-workers. This project extends the study of emotion regulation to others’ emotions as well as one’s own. The major project output will be an ev ....When, why, and how well do we regulate other people's emotions? This project aims to understand when and why people attempt to regulate others' emotions, and to evaluate which regulation processes are most effective. We will study regulation attempts as they occur over minutes, days, and months in interactions between romantic couples and between nurse co-workers. This project extends the study of emotion regulation to others’ emotions as well as one’s own. The major project output will be an evidence-based theory of extrinsic regulation. Project benefits include applications of this new knowledge to programs and policies that reduce negative emotions and stress in healthcare workers and couples, reducing workplace burnout, on-the-job errors, relationship breakdown and their associated economic costs.Read moreRead less
Binocular rivalry: a new model to measure it, and a new approach to attention and crossmodal influences. Ambiguity is inherent in visual perception. Retinal images under-specify the outside world and may suggest several interpretations, causing our perception to oscillate between them. This project will introduce a new and more objective method for quantifying this perceptual ambiguity and use it to explore the brain's response to ambiguous sensory inputs.
How satiation control reward value and cue-induced appetitive behaviours. This proposal aims to identify mechanisms that control environment-driven food-seeking behaviours. It seeks to do so by using modern virally-mediated and basic behavioural as well as histological techniques in a transgenic rat to characterise novel hindbrain circuits that control these feeding behaviours. This is significant as environment-driven overeating is problematic yet underlying mechanisms are unclear. This project ....How satiation control reward value and cue-induced appetitive behaviours. This proposal aims to identify mechanisms that control environment-driven food-seeking behaviours. It seeks to do so by using modern virally-mediated and basic behavioural as well as histological techniques in a transgenic rat to characterise novel hindbrain circuits that control these feeding behaviours. This is significant as environment-driven overeating is problematic yet underlying mechanisms are unclear. This project expects to provide new knowledge on when, where and how hindbrain neurons control environment-driven food-seeking behaviours. This should provide benefits to the advancement of knowledge on the neural mechanisms of food-seeking and provide a basic science platform for future research on the study of feeding behaviours.
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