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RCTs on Trial: How Placebo Effects Could Undermine Double-blind RCTs. Double-blind randomised placebo-controlled trials (RCTs) are considered the gold standard for establishing treatment efficacy. However, there are both theoretical and empirical reasons to believe that they do not adequately control for the placebo effect. Cost and ethical considerations prevent researchers conducting actual double-blind RCTs with patients from exploring these issues. To address this gap, this project uses nove ....RCTs on Trial: How Placebo Effects Could Undermine Double-blind RCTs. Double-blind randomised placebo-controlled trials (RCTs) are considered the gold standard for establishing treatment efficacy. However, there are both theoretical and empirical reasons to believe that they do not adequately control for the placebo effect. Cost and ethical considerations prevent researchers conducting actual double-blind RCTs with patients from exploring these issues. To address this gap, this project uses novel experimental models to systematically test key aspects of the double-blind RCT methodology that are intended to control for the placebo effect. The project aims to provide essential data on the validity of these trials, thereby improving Australia's health and ensuring that Government treatment subsidies are well spent.Read moreRead less
Memory consolidation - Integrating cognitive science and neuroscience approaches to how we remember and how we forget. How can we forget what happened yesterday, but vividly remember our first kiss? Neuroscientists think the brain has a special mechanism to strengthen memories with time, but many psychologists disagree. The project aims to bring the brain and the mind closer together, using the cutting-edge combination of brain imaging and psychological modelling.
Placing prediction into the fear circuit. How do we predict danger in our world? This project will identify the psychological mechanisms and brain pathways that allow us to learn to fear and to also overcome fear when it becomes pathological.
Effort and reward valuation. This project aims to examine the relationships between effort, value, and life satisfaction. Effort, which is closely akin to motivation, is influenced by several variables. The project will reveal the psychological variables that cause effort to have a positive as well as a negative influence on reward valuation. This will help to understand how, when, and why effort influences motivation, and how these processes may encourage healthier, more productive choices, and ....Effort and reward valuation. This project aims to examine the relationships between effort, value, and life satisfaction. Effort, which is closely akin to motivation, is influenced by several variables. The project will reveal the psychological variables that cause effort to have a positive as well as a negative influence on reward valuation. This will help to understand how, when, and why effort influences motivation, and how these processes may encourage healthier, more productive choices, and improved satisfaction with life.Read moreRead less
The role of reward expectancy and reward availability in appetitive motivation. This project will investigate the learning processes that help regulate our desire for rewards such as food and drugs and our decisions about when to pursue those rewards. The results will have implications for our understanding of normal reward motivation as well as interventions for maladaptive behaviours such as gambling and drug-taking.