ORCID Profile
0000-0003-1117-2409
Current Organisations
Bond University
,
Deakin University
,
Peter MacCallum Cancer Centre
,
EJ Whitten Centre for Prostate Cancer Research
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Publisher: Hindawi Limited
Date: 23-07-2019
DOI: 10.1111/HSC.12621
Abstract: Trauma in early childhood has been shown to adversely affect children's social, emotional, and physical development. Children living in out-of-home care (OoHC) have better outcomes when care providers are present for children, physically, psychologically, and emotionally. Unfortunately, the high turnover of out-of-home carers, due to vicarious trauma (frequently resulting in burnout and exhaustion) can result in a child's trauma being re-enacted during their placement in OoHC. Organisation-wide therapeutic care models (encompassing the whole organisation, from the CEO to all workers including administration staff) that are trauma-informed have been developed to respond to the complex issues of abuse and neglect experienced by children who have been placed in OoHC. These models incorporate a range of therapeutic techniques, and provide an overarching approach and common language that is employed across all levels of the organisation. The aim of this study was to investigate the current empirical evidence for organisation-wide, trauma-informed therapeutic care models in OoHC. A systematic review searching leading databases was conducted for evidence of organisation-wide, trauma-informed, out-of-home care studies, between 2002 and 2017. Seven articles were identified covering three organisational models. Three of the articles assessed the Attachment Regulation and Competency framework (ARC), one study assessed the Children and Residential Experiences programme (CARE), and three studies assessed The Sanctuary Model. Risk of bias was high in six of the seven studies. Only limited information was provided on the effectiveness of the models identified through this systematic review, although the evidence did suggest that trauma-informed care models may have significantly positive outcomes for children in OoHC. Future research should focus on evaluating components of trauma-informed care models and assessing the efficacy of the various organisational care models currently available.
Publisher: Wiley
Date: 27-09-2023
DOI: 10.1111/BJU.15883
Abstract: To provide a summary and discussion of international guidelines, position statements and consensus statements in relation to focal therapy (FT) for prostate cancer (PCa). The European Association of Urology‐European Association of Nuclear Medicine‐European Society for Radiotherapy and Oncology‐European Society of Urogential Radiology‐International Society of Urological Pathology‐International Society of Geriatric Oncology and American Urological Association‐American Society for Radiation Oncology‐Society of Urologic Oncology guidelines were interrogated for recommendations for FT. PubMed and Ovid Medline were searched for consensus statements. Only studies in English since 2015 were included. Reference lists of the included articles were also interrogated and a manual search for studies was also performed. Our results showed a lack of long‐term randomised data for FT. International Urological guidelines emphasised the need for more high‐quality clinical trials with robust oncological and toxicity outcomes. Consensus and positions statements were heterogenous. A globally accepted guideline for FT planning, technique and follow‐up are still yet to be determined. Well‐designed studies with long‐term follow‐up and robust clinical and toxicity endpoints are needed to improve our understanding of FT and create uniform guidelines to streamline management and follow‐up.
Publisher: Springer Science and Business Media LLC
Date: 12-2022
Publisher: Wiley
Date: 30-10-2023
DOI: 10.1111/BJU.16214
Publisher: Wiley
Date: 04-10-2023
DOI: 10.1111/BJU.16175
Publisher: Elsevier BV
Date: 10-2021
Publisher: Center for Open Science
Date: 17-08-2020
Abstract: The present study uses a qualitative approach to understand the impact of COVID-19 on family life. Australian parents of children aged 0-18 years were recruited via social media between April 8th and April 28th, 2020, when Australians were experiencing social distancing/isolation measures for the first time. As part of a larger survey, participants were asked to respond via an open-ended question about how COVID-19 had impacted their family. A total of 2,130 parents were included and represented a erse range of family backgrounds. Inductive template thematic analysis was used to understand patterns of meaning across the texts. Six themes were derived from the data, including: 'Boredom, depression and suicide: A spectrum of emotion' 'Families are missing the things that keep them healthy' 'Changing family relationships: The push pull of intimacy' 'The unprecedented demands of parenthood' 'The unequal burden of COVID-19' and 'Holding on to positivity'. Overall, the findings demonstrated a breadth of responses. Messages around loss and challenge were predominant, with many families reporting mental health difficulties and strained family relationships. However, not all families were negatively impacted by the restrictions, with some families reporting positive benefits and meaning, including opportunities for strengthening relationships, finding new hobbies, and developing positive characteristics such as appreciation, gratitude and tolerance.
Publisher: Wiley
Date: 03-2022
DOI: 10.1111/ANS.17337
Publisher: Wiley
Date: 21-09-2021
DOI: 10.1111/ANS.16325
Publisher: Springer Science and Business Media LLC
Date: 29-03-2022
DOI: 10.1007/S11701-022-01401-0
Abstract: Precise knowledge of each patient’s index cancer and surrounding anatomy is required for nerve-sparing robot-assisted radical prostatectomy (NS-RARP). Complementary to this, 3D printing has proven its utility in improving the visualisation of complex anatomy. This is the first systematic review to critically assess the potential of 3D printed patient-specific prostate cancer models in improving visualisation and the practice of NS-RARP. A literature search of PubMed and OVID Medline databases was performed using the terms “3D Printing”, “Robot Assisted Radical Prostatectomy” and related index terms as per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Eight articles were included six were identified via database searches, to which a further two articles were located via a snowballing approach. Eight papers were identified for review. There were five prospective single centre studies, one case series, one technical report and one letter to the editor. Of these articles, five publications (62.5%) reported on the utility of 3D printed models for NS-RARP planning. Two publications (25%) utilised 3D printed prostate models for simulation and training, and two publications (25%) used the models for patient engagement. Despite the nascency of the field, 3D printed models are emerging in the uro-oncological literature as a useful tool in visualising complex anatomy. This has proven useful in NS-RARP for preoperative planning, simulation and patient engagement. However, best practice guidelines, the future regulatory landscape, and health economic considerations need to be addressed before this synergy of new technologies is ready for the mainstream.
Publisher: Public Library of Science (PLoS)
Date: 11-02-2021
DOI: 10.1371/JOURNAL.PONE.0246058
Abstract: Recent research promotes comparing the current state of the environment with the past (and not the future) to increase the pro-environmental attitudes of those on the political right. We aimed to replicate this temporal framing effect and extend on research in this area by testing the potential drivers of the effect. Across two large-scale replication studies, we found limited evidence that past comparisons (relative to future comparisons) increase pro-environmentalism among those with a more conservative political ideology, thus precluding a full investigation into the mediators of the effect. Where the effect was present, it was not consistent across studies. In Study One, conservatives reported greater certainty that climate change was real after viewing past comparisons, as the environmental changes were perceived as more certain. However, in Study Two, the temporal framing condition interacted with political orientation to instead undermine the certainty about climate change among political liberals in the past-focused condition. Together, these studies present the first evidence of backfire from temporal frames, and do not support the efficacy of past comparisons for increasing conservatives’ environmentalism. We echo recent calls for open science principles, including preregistration and efforts to replicate existing work, and suggest the replication of other methods of inducing temporal comparisons.
Publisher: MDPI AG
Date: 13-12-2022
Abstract: PSMA PET-CT scans are now recommended in international urological guidelines for primary staging and re-staging of prostate cancer. However, there is little published literature on the clinical outcomes for patients after treatment decisions made using PSMA PET-CT results. This is a multisite, prospective cohort study investigating the clinical outcomes of men who received treatment plans based on PSMA PET-CT results for primary staging. Men with biopsy proven prostate cancer received a PSMA PET-CT scan for primary staging. Treatment plans were recommended by multidisciplinary teams (MDT). After treatment, these men were followed with 6 monthly PSA tests and imaging or biopsies if recommended by MDT. The primary outcome was treatment progression defined as the addition or change of any treatment modalities such as androgen deprivation therapy, radiation therapy or chemotherapy. In total, 80% of men did not have any treatment progression after enactment of treatment based on PSMA PET-CT primary staging results at 29 months of follow up. Men who had distant nodes seen on PSMA PET-CT had a 5 times increased risk of treatment progression. Larger studies with longer follow up are needed to validate our results and optimise the way clinicians use PSMA PET-CT results to guide management.
Publisher: Wiley
Date: 03-2019
DOI: 10.1111/JASP.12585
Publisher: Informa UK Limited
Date: 12-2019
DOI: 10.1111/AJPY.12271
Publisher: BMJ
Date: 09-2022
Abstract: A man in his 50s presented 4-week postirreversible electroporation (IRE) for low-to-intermediate risk prostate cancer with urinary symptoms, diarrhoea and passing fluid per rectum when urinating. Urine microscopy and sensitivities showed raised leucocytes, erythrocytes and pansensitive Escherichia coli . A CT cystogram revealed a rectourethral fistula (RUF). Urinary ersion with insertion of an indwelling catheter for 6 weeks was performed. A rigid cystoscopy 6 weeks after urinary ersion revealed that the fistula was still present, confirmed by intraoperative contrast. The fistula was repaired with diathermy and a fibrin glue. The patient reported resolution of urinary and bowel symptoms. This is the first case report in the literature of an RUF following IRE for prostate cancer. It is important to report these rare complications as novel treatments become more common across the world.Background
Publisher: Elsevier BV
Date: 12-2021
Publisher: MDPI AG
Date: 31-05-2022
Abstract: Prostate-specific membrane antigen (PSMA) positron emission tomography-computed tomography (PET-CT) is a novel imaging modality used to stage recurrent prostate cancer. It has the potential to improve prognostication and ultimately guide the timing of treatment for men with recurrent prostate cancer. This study aims to assess the clinical impact of PSMA PET-CT by analyzing its predictive value of treatment progression after 3 years of follow-up. In this prospective cohort study of 100 men, patients received a PSMA PET-CT for restaging of their disease which was used by a multi-disciplinary team to make a treatment decision. The primary endpoint was treatment progression. This was defined as the addition or change of any treatment modalities such as androgen deprivation therapy (ADT), radiation therapy or chemotherapy. The median follow-up time was 36 months (IQR 24–40 months). No treatment progression was found in 72 (75%) men and therefore 24 (25%) patients were found to have treatment progression. In men with a negative PSMA PET-CT result, 5/33 (15.1%) had treatment progression and 28/33 (84.8%) had no treatment progression. In conclusion, clinical decisions made with PSMA PET-CT results led to 75% of men having no treatment progression at 3 years of follow-up. In men with negative PSMA PET-CT results, this increased to 85% of men.
Publisher: Informa UK Limited
Date: 26-02-2023
Publisher: Wiley
Date: 07-08-2023
DOI: 10.1111/BJU.16139
Publisher: Informa UK Limited
Date: 08-2019
DOI: 10.1111/AP.12379
No related grants have been discovered for Sean Ong.