ORCID Profile
0000-0002-4887-8694
Current Organisations
Flinders University
,
University of Tasmania
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Publisher: IEEE
Date: 29-11-2020
Publisher: Elsevier BV
Date: 2023
Publisher: Elsevier BV
Date: 12-2012
DOI: 10.1016/J.MBS.2012.06.006
Abstract: A model is presented for characterizing the process by which cancellous bone changes in volume and structure over time. The model comprises simulations of local changes resulting from in idual remodelling events, known as bone multicellular units (BMU), and an ordinary differential equation for connecting the number of remodelling events to real time. The model is validated on micro-CT scans of tibiae of normal rats, estrogen deprived rats and estrogen deprived rats treated with bisphosphonates. The model explains the asymptotic trends seen in changes of bone volume over time resulting from estrogen deprivation as well as trends seen subsequent to treatment. The model demonstrates that both bone volume and structure changes can be explained in terms of resetting remodelling parameters. The model also shows that either current understanding of the effects of bisphosphonates is not correct or that the simplest description of remodelling does not suffice to explain both the change in bone volume and structure of rats treated with bisphosphonates.
Publisher: IEEE
Date: 11-2015
Publisher: Elsevier BV
Date: 05-2009
Publisher: Wiley
Date: 11-05-2023
DOI: 10.1111/AEC.13350
Abstract: We use fossil, sub‐fossil and contemporary records of the Broad‐toothed rat, Mastacomys fuscus , to model changes in its range over the last 21 thousand years. Mastacomys fuscus was exposed to, and flourished in, a much broader range of environmental conditions in the recent past than it occupies today. It also currently occupies a much smaller range than it did in the Late Pleistocene. Apart from a weak response to sea‐level rise in the Holocene, the decline of M. fuscus does not correlate with known climate change. Instead, the contraction of the species' distribution on mainland Australia to high‐elevation areas occurred recently and rapidly. Small changes in the 1000 year BP and present‐day projected distributions imply some contraction of the area of suitable climate to higher elevations of the mainland subspecies M. f. mordicus , up to 2200 m above sea level. However, M. f. mordicus also persists near sea level at Cape Otway (southwestern Victoria) and from sea level to 1500 m above sea level at Barrington Tops (eastern New South Wales, Australia). This suggests suitable habitat may still exist in coastal Victoria and the central Tablelands/Blue Mountains areas. This research highlights the importance and value of using sub‐fossil data to understand changes in the distribution and niche occupation of threatened species as the basis for conservation planning.
No related grants have been discovered for Brianna Martin.