ORCID Profile
0000-0002-8014-9117
Current Organisations
University of Melbourne
,
University of Tasmania
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: Elsevier BV
Date: 07-2023
Publisher: Environmental Health Perspectives
Date: 18-09-2022
Publisher: Environmental Health Perspectives
Date: 18-09-2022
Publisher: Research Square Platform LLC
Date: 23-06-2023
DOI: 10.21203/RS.3.RS-3045254/V1
Abstract: BACKGROUND Evidence on the relationship between air pollution and allergic sensitisation in childhood is inconsistent, and this relationship has not been investigated in the context of smoke events that are predicted to increase with climate change. Thus, we aimed to evaluate associations between exposure in two early life periods to severe levels of particulate matter with an aerodynamic diameter 2.5µm (PM 2.5 ) from a mine fire, background PM 2.5 , and allergic sensitisation later in childhood. METHODS We measured specific immunoglobulin E (IgE) levels for seven common aeroallergens as well as total IgE levels in a cohort of children who had been exposed to the Hazelwood coal mine fire, either in utero or during their first two years of life, in a regional area of Australia where ambient levels of PM 2.5 are generally low. We estimated personal exposure to fire-specific emissions of PM 2.5 based on a high-resolution meteorological and pollutant dispersion model and detailed reported movements of pregnant mothers and young children during the fire. We also estimated the usual background exposure to PM 2.5 at the residential address at birth using a national satellite-based land-use regression model. Associations between both sources of PM 2.5 and sensitisation to dust, cat, fungi, and grass seven years after the fire were estimated with logistic regression, while associations with total IgE levels were estimated with linear regression. RESULTS No association was found between the levels of exposure at either developmental stage to fire-related PM 2.5 and allergic sensitisation seven years after the event. However, levels of background exposure were positively associated with sensitisation to dust (OR = 1.89, 95%CI = 1.11,3.20 per 1 µg/m 3 ). CONCLUSIONS Chronic but low exposure to PM 2.5 in early life could be more strongly associated with allergic sensitisation in childhood than time-limited high exposure levels, such as the ones experienced during landscape fires.
Publisher: Center for Open Science
Date: 25-09-2023
Publisher: Elsevier BV
Date: 07-2022
DOI: 10.1016/J.ENVRES.2022.112969
Abstract: While the relationship between outdoor particulate matter (PM) and lower respiratory tract infections in children and adolescents is accepted, we know little about the impacts of outdoor PM on the risk of developing or aggravating upper respiratory tract infections (URTIs). We aimed to review the literature examining the relationship between outdoor PM exposure and URTIs in children and adolescents. A systematic search of EMBASE, MEDLINE, PubMed, Scopus, CINAHL and Web of Science databases was undertaken on April 3, 2020 and October 27, 2021. Comparable short-term studies of time-series or case-crossover designs were pooled in meta-analyses using random-effects models, while the remainder of studies were combined in a narrative analysis. Quality, risk of bias and level of evidence for health effects were appraised using a combination of emerging frameworks in environmental health. Out of 1366 articles identified, 34 were included in the systematic review and 16 of these were included in meta-analyses. Both PM This study found some evidence of associations between PM and URTIs in children and adolescents, the relationship strength increased with PM
No related grants have been discovered for Myriam Ziou.