ORCID Profile
0000-0001-5769-7281
Current Organisation
Deakin University
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Publisher: American Chemical Society (ACS)
Date: 02-12-2014
DOI: 10.1021/AM505849E
Abstract: "Thread-based microfluidics" research has so far focused on utilizing and manipulating the wicking properties of threads to form controllable microfluidic channels. In this study we aim to understand the separation properties of threads, which are important to their microfluidic detection applications for blood analysis. Confocal microscopy was utilized to investigate the effect of the microscale surface morphologies of fibers on the thread's separation efficiency of red blood cells. We demonstrated the remarkably different separation properties of threads made using silk and cotton fibers. Thread separation properties dominate the clarity of blood typing assays of the ABO groups and some of their weak subgroups (Ax and A3). The microfluidic thread-based analytical devices (μTADs) designed in this work were used to accurately type different blood s les, including 89 normal ABO and 6 weak A subgroups. By selecting thread with the right surface morphology, we were able to build μTADs capable of providing rapid and accurate typing of the weak blood groups with high clarity.
Publisher: Elsevier BV
Date: 03-2008
Publisher: Informa UK Limited
Date: 10-01-2004
Publisher: Wiley
Date: 03-07-2006
Publisher: Elsevier BV
Date: 07-1998
Publisher: Elsevier BV
Date: 07-2023
Publisher: Elsevier BV
Date: 04-2018
DOI: 10.1016/J.FOODCHEM.2017.12.022
Abstract: In this study, a paper-based microfluidic enzyme-linked immunosorbent assay (ELISA) was developed as a screening system for rapid detection of clenbuterol, which is illegally used as a growth promoter for food-producing animals. The microfluidic paper-based analytical device (μPAD) was combined with ELISA and the intrinsic properties of paper allowed the entrapment of antibody through cellulosic fibres, validating to be an alternative to 96-well ELISA microplate for food safety monitoring. Detection of clenbuterol in milk was achieved by measuring the intensity of colour change that was proportional to the analyte concentration with a detection limit of 0.2 ppb. The μPAD effectively reduces the cost, volume of reagents, and time required to run ELISA for food s le testing.
Publisher: IEEE
Date: 11-2011
Publisher: Springer Science and Business Media LLC
Date: 19-02-2019
Publisher: American Chemical Society (ACS)
Date: 26-04-2022
Abstract: Surface-enhanced Raman spectroscopy (SERS) has been identified as a fundamental surface-sensitive technique that boosts Raman scattering by adsorbing target molecules on specific surfaces. The application of SERS highly relies on the development of smart SERS substrates, and thus the fabrication of SERS substrates has been constantly improved. Herein, we investigate the impacts of different substrates on SERS technology including plasmonic metal nanoparticles, semiconductors, and hybrid systems in quantitative food safety and quality analysis. We first discuss the fundamentals, substrate designs, and applications of SERS. We then provide a critical review of the recent progress of SERS in its usage for screening and detecting chemical and biological contaminants including fungicides, herbicides, insecticides, hazardous colorants, and biohazards in food s les to assess the analytical capabilities of this technology. Finally, we investigate the future trends and provide practical techniques that could be used to fulfill the requirements for rapid analysis of food at a low cost.
Publisher: American Society for Microbiology
Date: 28-10-2020
DOI: 10.1128/AEM.01195-20
Abstract: Prevalence of C ylobacter in raw poultry remains a major food microbiological safety challenge. Novel mitigation strategies are required to ensure the safety and quality of poultry products. Active food packaging can control pathogens without directly adding antimicrobials into the food matrix and extend the food’s shelf life. The functionalized absorbing pad with ZnO NPs developed in this study was able to inactivate C. jejuni in raw chicken meat and keep the meat free from C. jejuni contamination during shelf life without any observed migration of nanoparticles. The controllable conversion of immobilized ZnO NPs to free Zn 2+ makes this approach safe and eco-friendly and paves the way for developing a novel intervention strategy for other high-risk foods. Our study applied nanotechnology to exploit an effective approach for C ylobacter control in raw chicken meat products.
Publisher: Springer Science and Business Media LLC
Date: 11-07-2015
DOI: 10.1007/S00216-015-8845-5
Abstract: A recently developed blood typing diagnostic based on a polyester thread substrate has shown great promise for use in medical emergencies and in impoverished regions. The device is easy to use and transport, while also being inexpensive, accurate, and rapid. This study used a fluorescent confocal microscope to delve deeper into how red blood cells were behaving within the polyester thread-based diagnostic at the cellular level, and how plasma separation could be made to visibly occur on the thread, making it possible to identify blood type in a single step. Red blood cells were stained and the plasma phase dyed with fluorescent compounds to enable them to be visualised under the confocal microscope at high magnification. The mechanisms uncovered were in surprising contrast with those found for a similar, paper-based method. Red blood cell aggregates did not flow over each other within the thread substrate as expected, but suffered from a restriction to their flow which resulted in the chromatographic separation of the RBCs from the liquid phase of the blood. It is hoped that these results will lead to the optimisation of the method to enable more accurate and sensitive detection, increasing the range of blood systems that can be detected.
Publisher: AIP Publishing
Date: 09-2013
DOI: 10.1063/1.4820413
Abstract: In this paper, we review the recent progress in the development of low-cost microfluidic devices based on multifilament threads and textiles for semi-quantitative diagnostic and environmental assays. Hydrophilic multifilament threads are capable of transporting aqueous and non-aqueous fluids via capillary action and possess desirable properties for building fluid transport pathways in microfluidic devices. Thread can be sewn onto various support materials to form fluid transport channels without the need for the patterned hydrophobic barriers essential for paper-based microfluidic devices. Thread can also be used to manufacture fabrics which can be patterned to achieve suitable hydrophilic-hydrophobic contrast, creating hydrophilic channels which allow the control of fluids flow. Furthermore, well established textile patterning methods and combination of hydrophilic and hydrophobic threads can be applied to fabricate low-cost microfluidic devices that meet the low-cost and low-volume requirements. In this paper, we review the current limitations and shortcomings of multifilament thread and textile-based microfluidics, and the research efforts to date on the development of fluid flow control concepts and fabrication methods. We also present a summary of different methods for modelling the fluid capillary flow in microfluidic thread and textile-based systems. Finally, we summarized the published works of thread surface treatment methods and the potential of combining multifilament thread with other materials to construct devices with greater functionality. We believe these will be important research focuses of thread- and textile-based microfluidics in future.
Publisher: Royal Society of Chemistry (RSC)
Date: 2012
DOI: 10.1039/C1LC20764D
Abstract: This paper describes the fabrication of microfluidic cloth-based analytical devices (μCADs) using a simple wax patterning method on cotton cloth for performing colorimetric bioassays. Commercial cotton cloth fabric is proposed as a new inexpensive, lightweight, and flexible platform for fabricating two- (2D) and three-dimensional (3D) microfluidic systems. We demonstrated that the wicking property of the cotton microfluidic channel can be improved by scouring in soda ash (Na(2)CO(3)) solution which will remove the natural surface wax and expose the underlying texture of the cellulose fiber. After this treatment, we fabricated narrow hydrophilic channels with hydrophobic barriers made from patterned wax to define the 2D microfluidic devices. The designed pattern is carved on wax-impregnated paper, and subsequently transferred to attached cotton cloth by heat treatment. To further obtain 3D microfluidic devices having multiple layers of pattern, a single layer of wax patterned cloth can be folded along a predefined folding line and subsequently pressed using mechanical force. All the fabrication steps are simple and low cost since no special equipment is required. Diagnostic application of cloth-based devices is shown by the development of simple devices that wick and distribute microvolumes of simulated body fluids along the hydrophilic channels into reaction zones to react with analytical reagents. Colorimetric detection of bovine serum albumin (BSA) in artificial urine is carried out by direct visual observation of bromophenol blue (BPB) colour change in the reaction zones. Finally, we show the flexibility of the novel microfluidic platform by conducting a similar reaction in a bent pinned μCAD.
Publisher: Elsevier BV
Date: 07-2003
Publisher: American Chemical Society (ACS)
Date: 12-12-2016
Publisher: Elsevier BV
Date: 10-2007
Publisher: Bentham Science Publishers Ltd.
Date: 08-2006
Publisher: Wiley
Date: 18-04-2016
Publisher: Elsevier BV
Date: 03-2015
Publisher: IEEE
Date: 11-2011
Publisher: American Scientific Publishers
Date: 03-2013
Publisher: MDPI AG
Date: 13-07-2009
Publisher: American Chemical Society (ACS)
Date: 04-10-2007
DOI: 10.1021/AR700065S
Publisher: American Chemical Society (ACS)
Date: 09-07-2009
DOI: 10.1021/LA901526E
Publisher: AIP
Date: 2011
DOI: 10.1063/1.3592463
Publisher: Elsevier BV
Date: 2022
DOI: 10.1016/J.BIOS.2021.113690
Abstract: Soft robotics have substantial benefits of safety, adaptability, and cost efficiency compared to conventional rigid robotics. Textiles have applications in soft robotics either as an auxiliary material to reinforce the conventional soft material or as an active soft material. Textiles of various types and configurations have been fabricated into key components of soft robotics in adaptable formats. Despite significant advancements, the efficiency and characteristics of textile actuators in practical applications remain unsatisfactory. To address these issues, novel structural and material designs as well as new textile technologies have been introduced. Herein, we aim at giving an insight into the current state of the art in textile technology for soft robotic manufacturing. We firstly discuss the fundamental actuation mechanisms for soft robotics. We then provide a critical review on the recently developed functional textiles as reinforcements, sensors, and actuators in soft robotics. Finally, the future trends and current strategies that can be employed in textile-based actuator manufacturing process have been explored to address the critical challenges in soft robotics.
Publisher: American Chemical Society (ACS)
Date: 27-07-2007
DOI: 10.1021/LA701035G
Publisher: American Scientific Publishers
Date: 10-2011
Publisher: Wiley
Date: 07-2008
Publisher: Springer Science and Business Media LLC
Date: 29-01-2015
Publisher: Royal Society of Chemistry (RSC)
Date: 2010
DOI: 10.1039/C0OB00306A
Publisher: Wiley
Date: 18-12-2007
Abstract: Silver(I) acetylides facilitate direct carbon–carbon bond formation at the bridgehead position of adamantane, and in some instances related systems such as carborate anions and bicyclo[2.2.2]octanes. Substrate constraints along with attempts to further understand the underlying mechanism are presented. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Publisher: Elsevier BV
Date: 03-2018
Publisher: American Chemical Society (ACS)
Date: 06-02-2015
DOI: 10.1021/ACS.ANALCHEM.5B00040
Abstract: If a paper-based analytical device (μ-PAD) could be made by printing indicators for detection of heavy metals in chemical symbols of the metals in a style of the periodic table of elements, it could be possible for such μ-PAD to report the presence and the safety level of heavy metal ions in water simultaneously and by text message. This device would be able to provide easy solutions to field-based monitoring of heavy metals in industrial wastewater discharges and in irrigating and drinking water. Text-reporting could promptly inform even nonprofessional users of the water quality. This work presents a proof of concept study of this idea. Cu(II), Ni(II), and Cr(VI) were chosen to demonstrate the feasibility, specificity, and reliability of paper-based text-reporting devices for monitoring heavy metals in water.
Publisher: Royal Society of Chemistry (RSC)
Date: 2010
DOI: 10.1039/B923890P
Publisher: Elsevier BV
Date: 05-2018
Publisher: Elsevier BV
Date: 02-2014
Publisher: American Chemical Society (ACS)
Date: 02-05-2008
DOI: 10.1021/LA800435D
Publisher: Elsevier BV
Date: 10-2005
Publisher: American Chemical Society (ACS)
Date: 03-2005
DOI: 10.1021/OL050121+
Publisher: Wiley
Date: 04-2009
DOI: 10.1002/MRC.2401
Publisher: The Royal Society of Chemistry
Date: 14-07-2017
DOI: 10.1039/9781788010528-00121
Abstract: The screening of biological contaminants, chemical hazards and allergens in food products is critical to understanding the potential negative effects on human health. Intensive research has been conducted to develop various detection methods to monitor food safety and quality. However, most of these developed methods are costly and require supporting equipment and professional skills to perform the testing. Therefore, there is high demand to develop alternative and innovative methods that are affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free and deliverable to fulfil the “ASSURED” criteria set by the World Health Organization (WHO). Colorimetric analysis can identify and determine the content of chemical elements/compounds in s le solutions by using various color reagents. This method has been used to detect and quantify specific pathogens, chemicals and hazards in foods for safety and quality control, which are suitable for use in laboratories and field studies. This chapter summarizes the recent advances in colorimetric analysis for assessing food safety and quality assurance, such as colorimetric detection of pathogens, toxins, parasites, antibiotic residues and chemical hazards in agri-food products. This chapter also conveys the current technical limitations and strategic research of colorimetric analysis required to further improve the performance of analytical assays in sensing food safety and quality control.
Publisher: Elsevier BV
Date: 06-2003
Publisher: Elsevier BV
Date: 2019
DOI: 10.1016/J.ACA.2018.09.041
Abstract: This work demonstrates a sensitive and rapid method for the detection of antibiotic residues in food s les by employing the filtration behaviour of paper combined with aggregation and precipitation of chemical reagents. Using this concept, we successfully determined the presence of oxytetracycline and norfloxacin residues in pork using metal complexation on microfluidic paper-based analytical devices (μPADs). The base substrate (top layer of the device) was fabricated by printing letter channels of the words "oxytetracycline" and "norfloxacin" before functionalization with copper (II) sulfate pentahydrate in 0.5 M sodium hydroxide and iron (III) nitrate nanohydrate in 5 mM ammonia solution for the detection of oxytetracycline and norfloxacin separately. A transition metal hydroxide formed upon reaction that created solid precipitates on paper and allowed antibiotic residues to bind to the metal ions via coordination chemistry. The metal ion-antibiotic complex could form on the filter paper and generated a visible color change with the detection limit of 1 ppm for both oxytetracycline and norfloxacin in pork. This procedure of filtration and concentration in combination with a simple text-reporting approach allows the end users to achieve a low limit of detection as well as easy result interpretation in food safety monitoring.
Publisher: American Scientific Publishers
Date: 05-2013
Publisher: IEEE
Date: 02-2010
Publisher: Elsevier BV
Date: 03-2009
Publisher: Informa UK Limited
Date: 20-09-2004
Publisher: Informa UK Limited
Date: 10-05-2004
Publisher: American Chemical Society (ACS)
Date: 19-11-2021
Publisher: Royal Society of Chemistry (RSC)
Date: 2009
DOI: 10.1039/B909171H
Abstract: The effect on the rate of reaction of each of a series of Menschutkin processes on changing from a molecular solvent to an ionic liquid was investigated. In each case, the rate acceleration observed at room temperature could be attributed to the change in the entropy of the system on reaching the transition state, offsetting any enthalpic cost.
Publisher: Royal Society of Chemistry (RSC)
Date: 2002
DOI: 10.1039/C5OB02598B
Abstract: An ionic liquid significantly increases benzylic carbocation formation due to favourable ionic liquid–transition state interactions. The magnitude of transition state solvation was shown to be critical, explaining the difference between this and previous cases.
Publisher: Elsevier BV
Date: 06-2015
Publisher: Elsevier BV
Date: 2016
Publisher: Elsevier BV
Date: 11-2005
Publisher: BioResources
Date: 23-01-2015
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C5RA01468A
Abstract: This study presents a low-cost method for separating blood plasma on μPADs.
Publisher: Elsevier BV
Date: 06-2020
Publisher: Wiley
Date: 28-04-2020
Publisher: CSIRO Publishing
Date: 1995
DOI: 10.1071/CH9951379
Abstract: From intermolecular and intramolecular competition experiments, it has been established that, by comparison with an N-methyl substituent, an N-acetyl group deactivates glycine residues in piperazine-2,5-diones towards free-radical bromination. Combined with the ease of introduction and removal of N-acetyl substituents, the deactivating effect provides a method for regiocontrolled functionalization of these compounds.
Publisher: Wiley
Date: 29-06-2009
Publisher: Ivyspring International Publisher
Date: 2018
DOI: 10.7150/THNO.22573
Publisher: Royal Society of Chemistry (RSC)
Date: 2008
DOI: 10.1039/B805255G
Abstract: Temperature dependent rate studies demonstrate an enthalpic benefit and an entropic cost associated with the change in the rate of a unimolecular substitution process on addition of a high proportion of an ionic liquid, the latter effect being supported by molecular dynamics simulations.
Publisher: Elsevier BV
Date: 07-2020
Publisher: IEEE
Date: 02-2010
Publisher: American Chemical Society (ACS)
Date: 20-10-2016
DOI: 10.1021/LA803710D
Publisher: Royal Society of Chemistry (RSC)
Date: 2007
DOI: 10.1039/B705571D
No related grants have been discovered for Azadeh Nilghaz.