ORCID Profile
0000-0001-5819-765X
Current Organisation
Deakin University
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Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-2022
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 02-2023
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2023
Publisher: Elsevier BV
Date: 02-2020
Publisher: MDPI AG
Date: 31-12-2022
Abstract: We consider multipath TCP (MPTCP) flows over the data networking dynamics of IEEE 802.11ay for drone surveillance of areas using high-definition video streaming. Mobility-induced handoffs are critical in IEEE 802.11ay (because of the smaller coverage of mmWaves), which adversely affects the performance of such data streaming flows. As a result of the enhanced 802.11ay network events and features (triggered by beamforming, channel bonding, MIMO, mobility-induced handoffs, channel sharing, retransmissions, etc.), the time taken for packets to travel end-to-end in 802.11ay are inherently time-varying. Several fundamental assumptions inherent in stochastic TCP models, including Poisson arrivals of packets, Gaussian process, and parameter certainty, are challenged by the improved data traffic dynamics over IEEE 802.11ay networks. The MPTCP model’s state estimation differs largely from the actual network values. We develop a new data-driven stochastic framework to address current deficiencies of MPTCP models and design a foundational architecture for intelligent multipath scheduling (at the transport layer) considering lower layer (hybrid) beamforming. At the heart of our cross-layer architecture is an intelligent learning agent for actuating and interfacing, which learns from experience optimal packet cloning, scheduling, aggregation, and beamforming using successful features of multi-armed bandits and federated learning. We demonstrate that the proposed framework can estimate and optimize jointly (explore–exploit) and is more practicable for designing the next generation of low-delay and robust MPTCP models.
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2022
Publisher: Springer Science and Business Media LLC
Date: 29-04-2021
DOI: 10.1038/S41564-021-00892-1
Abstract: Many wastewater treatment plants around the world suffer from the operational problem of foaming. This is characterized by a persistent stable foam that forms on the aeration basin, which reduces effluent quality. The foam is often stabilized by a highly hydrophobic group of Actinobacteria known as the Mycolata
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 05-2016
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 03-2022
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-2021
Publisher: MDPI AG
Date: 08-10-2020
DOI: 10.3390/V12101138
Abstract: Achromobacter spp. are becoming increasingly associated with lung infections in patients suffering from cystic fibrosis (CF). A. marplatensis, which is closely related to A. xylosoxidans, has been isolated from the lungs of CF patients and other human infections. This article describes the isolation, morphology and characterization of two lytic bacteriophages specific for an A. marplatensis strain isolated from a pneumonia patient. This host strain was the causal agent of hospital acquired pneumonia–the first clinical report of such an occurrence. Full genome sequencing revealed bacteriophage genomes ranging in size from 45901 to 46,328 bp. Transmission electron microscopy revealed that the two bacteriophages AMA1 and AMA2 belonged to the Siphoviridae family. Host range analysis showed that their host range did not extend to A. xylosoxidans. The possibility exists for future testing of such bacteriophages in the control of Achromobacter infections such as those seen in CF and other infections of the lungs. The incidence of antibiotic resistance in this genus highlights the importance of seeking adjuncts and alternatives in CF and other lung infections.
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2022
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 07-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2020
Publisher: Oxford University Press (OUP)
Date: 10-2022
DOI: 10.1111/LAM.13742
Abstract: The production of a stable foam on the surfaces of reactors is a global operating problem in activated sludge plants. In many cases, these foams are stabilized by hydrophobic members of the Mycolata, a group of Actinobacteria whose outer membranes contain long-chain hydroxylated mycolic acids. There is currently no single strategy which works for all foams. One attractive approach is to use lytic bacteriophages specific for the foam stabilizing Mycolata population. Such phages are present in activated sludge mixed liquor and can be recovered readily from it. However, no phage has been recovered which lyses Gordonia amarae and Gordonia pseudoamarae, probably the most common foaming Mycolata members. Whole genome sequencing revealed that both G. amarae and G. pseudoamarae from plants around the world are particularly well endowed with genes encoding antiviral defence mechanisms. However, both these populations were lysed rapidly by a parasitic nanobacterium isolated from a plant in Australia. This organism, a member of the Saccharibacteria, was also effective against many other Mycolata, thus providing a potential agent for control of foams stabilized by them.
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 11-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2022
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-01-2023
DOI: 10.36227/TECHRXIV.21836388
Abstract: The work is related to the privacy of smart meter and the benifits of using URLLC in smart grid network.
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2023
Publisher: Microbiology Society
Date: 18-10-2022
Abstract: The taxonomic status of two Gordonia strains, designated BEN371 and CON9 T , isolated from stable foams on activated sludge plants was the subject of a polyphasic study which also included the type strains of Gordonia species and three authenticated Gordonia amarae strains recovered from such foams. Phylogenetic analyses of 16S rRNA gene sequences showed that these isolates formed a compact cluster suggesting a well-supported lineage together with a second branch containing the G. amarae strains. A phylogenomic tree based on sequences of 92 core genes extracted from whole genome sequences of the isolates, the G. amarae strains and Gordonia type strains confirmed the assignment of the isolates and the G. amarae strains to separate but closely associated lineages. Average nucleotide index (ANI) and digital DNA–DNA hybridisation (dDDH) similarities showed that BEN371 and CON9 T belonged to the same species and had chemotaxonomic and morphological features consistent with their assignment to the genus Gordonia . The isolates and the G. amarae strains were distinguished using a range of phenotypic features and by low ANI and dDDH values of 84.2 and 27.0 %, respectively. These data supplemented with associated genome characteristics show that BEN371 and CON9 T represent a novel species of the genus Gordonia . The name proposed for members of this taxon is Gordonia pseudamarae sp. nov. with isolate CON9 T (=DSM 43602 T =JCM 35249 T ) as the type strain.
Publisher: IEEE
Date: 06-2022
Publisher: MDPI AG
Date: 12-07-2019
Abstract: Bacteriophages (phages) are biological entities that have attracted a great deal of attention in recent years. They have been reported as the most abundant biological entities on the planet and their ability to impact the composition of bacterial communities is of great interest. In this review, we aim to explore where phages exist in natural and artificial environments and how they impact communities. The natural environment in this review will focus on the human body, soils, and the marine environment. In these naturally occurring environments there is an abundance of phages suggesting a role in the maintenance of bacterial community homeostasis. The artificial environment focuses on wastewater treatment plants, industrial processes, followed by pharmaceutical formulations. As in natural environments, the existence of bacteria in manmade wastewater treatment plants and industrial processes inevitably attracts phages. The presence of phages in these environments can inhibit the bacteria required for efficient water treatment or food production. Alternatively, they can have a positive impact by eliminating recalcitrant organisms. Finally, we conclude by describing how phages can be manipulated or formulated into pharmaceutical products in the laboratory for use in natural or artificial environments.
Publisher: IEEE
Date: 04-2020
Publisher: Springer Science and Business Media LLC
Date: 25-09-2020
Publisher: American Society for Microbiology
Date: 09-04-2020
DOI: 10.1128/MRA.00030-20
Abstract: We report the complete genome sequence of Moraxella osloensis strain YV1, which was isolated from a wastewater treatment plant in Australia. The YV1 genome comprises a 2,615,801-bp chromosome and four plasmids. Moraxella osloensis strain YV1 displays the distinctive morphology of Eikelboom morphotype 1863.
Publisher: IEEE
Date: 04-2019
Publisher: Elsevier BV
Date: 12-2021
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2020
Publisher: IEEE
Date: 11-2012
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 07-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2020
Publisher: IEEE
Date: 09-2015
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 12-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-01-2023
DOI: 10.36227/TECHRXIV.21836388.V1
Abstract: The work is related to the privacy of smart meter and the benifits of using URLLC in smart grid network.
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2023
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 15-08-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2022
Publisher: MDPI AG
Date: 06-08-2021
DOI: 10.3390/V13081557
Abstract: Bacillus is a highly erse genus containing over 200 species that can be problematic in both industrial and medical settings. This is mainly attributed to Bacillus sp. being intrinsically resistant to an array of antimicrobial compounds, hence alternative treatment options are needed. In this study, two bacteriophages, PumA1 and PumA2 were isolated and characterized. Genome nucleotide analysis identified the two phages as novel at the DNA sequence level but contained proteins similar to phi29 and other related phages. Whole genome phylogenetic investigation of 34 phi29-like phages resulted in the formation of seven clusters that aligned with recent ICTV classifications. PumA1 and PumA2 share high genetic mosaicism and form a genus with another phage named WhyPhy, more recently isolated from the United States of America. The three phages within this cluster are the only candidates to infect B. pumilus. Sequence analysis of B. pumilus phage resistant mutants revealed that PumA1 and PumA2 require polymerized and peptidoglycan bound wall teichoic acid (WTA) for their infection. Bacteriophage classification is continuously evolving with the increasing phages’ sequences in public databases. Understanding phage evolution by utilizing a combination of phylogenetic approaches provides invaluable information as phages become legitimate alternatives in both human health and industrial processes.
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2023
Publisher: Association for Computing Machinery (ACM)
Date: 15-09-2023
DOI: 10.1145/3609503
Abstract: The Internet of Things (IoT) and Distributed ledger technology (DLT) have significantly changed our daily lives. Due to their distributed operational environment and naturally decentralized applications, the convergence of these two technologies indicates a more lavish arrangement for the future. This article develops a comprehensive survey to investigate and illustrate state-of-the-art DLT for various IoT use cases, from smart homes to autonomous vehicles and smart cities. We develop a novel framework for conducting a systematic and comprehensive review of DLT over IoT by extending the knowledge graph approach. With relevant insights from this review, we extract innovative and pragmatic techniques to DLT design that enable high-performance, sustainable, and highly scalable IoT systems. Our findings support designing an end-to-end IoT-native DLT architecture for the future that fully coordinates network-assisted functionalities.
Publisher: IEEE
Date: 07-2013
Publisher: Zenodo
Date: 2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2021
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2020
Publisher: Springer Science and Business Media LLC
Date: 28-11-2022
DOI: 10.1186/S12864-022-09023-4
Abstract: Bacteriophages are widely considered to be highly abundant and genetically erse, with their role in the evolution and virulence of many pathogens becoming increasingly clear. Less attention has been paid on phages preying on Bacillus , despite the potential for some of its members, such as Bacillus anthracis , to cause serious human disease. We have isolated five phages infecting the causative agent of anthrax, Bacillus anthracis . Using modern phylogenetic approaches we place these five new Bacillus phages, as well as 21 similar phage genomes retrieved from publicly available databases and metagenomic datasets into the Tyrovirus group, a newly proposed group named so due to the conservation of three distinct tyrosine recombinases. Genomic analysis of these large phages (~ 160–170 kb) reveals their DNA packaging mechanism and genomic features contributing to virion morphogenesis, host cell lysis and phage DNA replication processes. Analysis of the three tyrosine recombinases suggest Tyroviruses undergo a prophage lifecycle that may involve both host integration and plasmid stages. Further we show that Tyroviruses rely on ergent invasion mechanisms, with a subset requiring host S-layer for infection. Ultimately, we expand upon our understanding on the classification, phylogeny, and genomic organisation of a new and substantial phage group that prey on critically relevant Bacillus species. In an era characterised by a rapidly evolving landscape of phage genomics the deposition of future Tyroviruses will allow the further unravelling of the global spread and evolutionary history of these Bacillus phages.
Publisher: Elsevier BV
Date: 2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 11-2021
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2015
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2020
Publisher: MDPI AG
Date: 29-08-2022
DOI: 10.3390/FI14090257
Abstract: There is no well-defined utility function for existing multipath TCP algorithms. Therefore, network utility maximization (NUM) for MPTCP is a complex undertaking. To resolve this, we develop a novel condition under which Kelly’s NUM mechanism may be used to explicitly compute the equilibrium. We accomplish this by defining a new utility function for MPTCP by employing Tullock’s rent-seeking paradigm from game theory. We investigate the convergence of no-regret learning in the underlying network games with continuous actions. Based on our understanding of the design space, we propose an original MPTCP algorithm that generalizes existing algorithms and strikes a good balance among the important properties. We implemented this algorithm in the Linux kernel, and we evaluated its performance experimentally.
Publisher: Springer International Publishing
Date: 2022
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 03-2018
Publisher: IEEE
Date: 04-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2018
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 12-2019
Publisher: American Society for Microbiology
Date: 15-06-2023
DOI: 10.1128/SPECTRUM.05332-22
Abstract: Amid the global antibiotic resistance crisis, novel antimicrobials are needed to treat problematic bacterial infections, including those from the Burkholderia cepacia complex. One such alternative is the use of bacteriophages however, a lot is still unknown about their biology.
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2023
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 07-2021
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2017
Publisher: Elsevier BV
Date: 02-2021
No related grants have been discovered for Shiva Pokhrel.