Website
http://dataportal.arc.gov.au/NCGP/API/grants/IN180100005
Funding Status
Active
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Funded Activity Summary
Turning back the clock on brain cell aging. This proposal aims to determine the role of fundamental epigenetic mechanisms in the process of aging and whether modulation of the epi-genome underpins an improvement in cognitive function. It combines the fields of epigenetics, neurosciences and mathematics to delineate the dynamics of DNA methylation and histone modification marking on the transcriptome during normal, healthy aging. The outcomes will provide significant new knowledge of the variable cognitive decline that occurs in healthy aging and why some populations age less successfully than others do. Better understanding of the impact of environmental change on the biology of aging has potential community benefits.Funded Activity Details
Start Date: 2019
End Date: 12-2024
Funding Scheme: Discovery Indigenous
Funding Amount: $458,608.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Epigenetics (incl. Genome Methylation and Epigenomics) | Bioinformatics | Genetics | Cell Neurochemistry
ANZSRC Socio-Economic Objective (SEO)
Ageing and Older People | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Mathematical Sciences |
