Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP0664792
Funding Status
Closed
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Funded Activity Summary
Nucleophilic carbenes as organocatalysts for asymmetric synthesis. Chemical compounds which come in two chiral mirror images (enantiomers) can have very different biological function. Often one form can have beneficial effects while the other can cause great harm (such as birth defects in the case of thalidomide). It is therefore very important for the drug industry to have asymmetric chemical reactions that lead specifically to only one enantiomer. The asymmetric reactions in this project have been used previously to synthesise the anti-cancer metabolite roseophilin. The results of this project will ensure that there are many more similar success stories in the pharmaceutical and biotechnology industries.Funded Activity Details
Start Date: 2006
End Date: 03-2010
Funding Scheme: Discovery Projects
Funding Amount: $240,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Organic Chemistry | Physical Organic Chemistry | Mechanisms Of Reactions | Quantum Chemistry
