Discovery Projects - Grant ID: DP160102582

Funding Activity

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Funded Activity Summary

Investigating why malaria parasites have a unique translocon. This project aims to explore the mechanism that enables malaria parasites to thrive in their host cells. Parasites that cause the disease malaria reside inside erythrocytes, a very basic cell that lacks a vesicular trafficking pathway. To survive and thrive in this environment, the parasite has evolved a completely unique cell biological phenomenon termed PTEX to transport its proteins into the host cell. The aim of this project is to determine how this novel PTEX machinery exports proteins into erythrocytes and whether PTEX is also required for parasite survival during the initial stages of a host infection when malaria reside in hepatocytes.

Funded Activity Details

Start Date: 06-2016

End Date: 12-2019

Funding Scheme: Discovery Projects

Funding Amount: $350,100.00

Funder: Australian Research Council