Linkage Projects - Grant ID: LP0219617

Funding Activity

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Funded Activity Summary

Exploitation of a Novel Drug Target for Controlling Animal Trypanosomiasis. Trypanosomiasis greatly reduces livestock productivity in countries where it is endemic and is a threat to livestock and native wildlife in countries such as Australia where it is exotic but there is a risk of entry. New trypanocidal drugs with different modes of action are urgently needed to overcome growing resistance. This project aims to characterise trypanosome tubulin and, with this information, produce new tubulin-binding compounds for assessment in vitro and in vivo. Upon completion of the project it is expected that drug binding sites on trypanosome tubulin will be characterised and at least one candidate for clinical trials identified.

Funded Activity Details

Start Date: 07-2002

End Date: 12-2004

Funding Scheme: Linkage Projects

Funding Amount: $379,493.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Veterinary Sciences | Veterinary Medicine | Pharmacology | Parasitology

ANZSRC Socio-Economic Objective (SEO)

Biological sciences |